Chennai-based Endovascular & IR Specialist, Dr. Ravindran Ramalingam offers minimally invasive, scar-free treatments ensuring faster recovery and minimal pain.

Endovascular &
IR Specialist

Center Address
- Gleneagles Health City, Perumbakkam, Chennai, TN
- Maruti Scans, Velachery, Chennai, TN

Chemoembolization (TACE)

A Targeted, Minimally Invasive Treatment to Control Liver Tumors

When cancer affects the liver—especially primary liver cancer (Hepatocellular Carcinoma) or tumors that have spread to the liver—not everyone can have surgery.

Transarterial Chemoembolization (TACE) is a minimally invasive, image-guided treatment that delivers chemotherapy directly to the tumor and blocks its blood supply, helping to shrink or control the tumor while protecting the rest of the body from high doses of chemotherapy.

👉Have a liver tumor and told surgery isn’t possible right now?

What Is Transarterial Chemoembolization?

Transarterial Chemoembolization (TACE) is a procedure where:

  • Chemotherapy is delivered directly into the artery feeding the tumor, and
  • That artery is then blocked (embolized) to cut off the tumor’s blood supply.

This double action:

  • Traps the chemotherapy inside the tumor
  • Starves the tumor of oxygen and nutrients
  • Reduces side effects compared to chemotherapy given through the vein
  • Helps shrink or control tumor growth

TACE is most commonly used for:

  • Liver cancer (Hepatocellular carcinoma)
  • Liver metastases from other cancers (in selected cases)
  • Targeted treatment

  • Minimally invasive

  • No big surgery

  • Faster recovery

  • Can be repeated if needed

Why Is Transarterial Chemoembolization Done?

TACE is done when:

  • Liver cancer cannot be removed by surgery
  • The tumor is too large or too many for ablation alone
  • The goal is to shrink the tumor before surgery or transplant
  • The aim is to control cancer growth and improve survival
  • The patient needs local treatment with fewer whole-body side effects

Main goals:

  • Control or shrink the tumor
  • Slow disease progression
  • Improve quality of life
  • Sometimes bridge the patient to surgery or liver transplant

How Is Transarterial Chemoembolization Done?

TACE is performed by an interventional radiologist in a cath lab using X-ray guidance.

Step-by-step:

  • You lie comfortably; local anesthesia (and sometimes sedation) is given
  • A small puncture is made in the groin or arm artery
  • A thin tube (catheter) is guided to the artery supplying the liver tumor
  • Chemotherapy drug is injected directly into the tumor’s blood supply
  • Then embolization material (particles) is injected to block the artery
  • This keeps the drug inside the tumor and cuts off blood flow
  • The catheter is removed, and a small dressing is applied

What Are the Risks?

TACE is widely used and generally safe in experienced centers. Possible risks with approximate incidence include:

  • Post-embolization syndrome (fever, pain, nausea, fatigue) – common (30–60%)
  • Abdominal pain – common (20–40%)
  • Nausea or vomiting – common (20–30%)
  • Temporary rise in liver enzymes – common (20–40%)
  • Infection or liver abscess – uncommon (<2–5%)
  • Bleeding or bruising at puncture site – uncommon (5–10%)
  • Liver failure (in weak livers) – rare (<1–3%, depends on liver condition)
  • Non-target embolization (affecting nearby organs) – rare (<1–2%)
Chemoembolization TACE Chennai – Procedure & Benefits

What Are the Alternatives?

Your treatment options depend on:

  • Your overall health and liver function
  • The size, number, and location of the liver tumors
  • Whether the cancer has spread
  • Your personal preferences and treatment goals

In many cases, a combination of treatments may offer the best results.

Alternative 1: No Active Treatment (Supportive Care)

  • Avoids procedures and cancer medicines
  • May be considered in very advanced disease or when treatment risks are too high
  • Main drawback: the cancer is likely to continue growing and spreading

Alternative 2: TARE (Transarterial Radioembolization)

  • A minimally invasive, image-guided treatment
  • Tiny beads are delivered into the liver tumor’s blood supply
  • These beads release radiation directly inside the tumor
  • Similar to TACE, but uses radiation instead of chemotherapy
  • Helps control tumor growth while limiting damage to healthy liver tissue

Alternative 3: Tumor Ablation

  • Another minimally invasive, image-guided procedure
  • A thin probe (wand) is placed through the skin into the tumor
  • Uses heat or cold to destroy cancer cells
  • Best suited for small or limited number of liver tumors

Alternative 4: Surgery or Liver Transplant

  • Surgery may involve removing part of the liver containing the tumor
  • In selected patients, liver transplantation may be an option
  • Can offer a potential cure in suitable cases
  • However, surgery:
    • Is major and invasive
    • Requires longer recovery
    • Not suitable for all patients due to liver function or tumor spread

Alternative 5: External Beam Radiation Therapy

  • Uses high-energy radiation beams directed at the tumor from outside the body
  • Given in multiple treatment sessions
  • Can help shrink tumors or relieve symptoms
  • Less commonly used as a first-line treatment for liver cancer

Alternative 6: Cancer Medicines and Immunotherapy

  • Includes targeted therapy, chemotherapy, and immunotherapy
  • Helps:
    • Slow tumor growth
    • Shrink tumors
    • Support the immune system in fighting cancer
  • Commonly used for advanced or spread liver cancer
  • May cause side effects and usually requires ongoing treatment

Choosing the Right Liver Cancer Treatment

Modern liver cancer care often uses a multidisciplinary approach, combining minimally invasive procedures, surgery, radiation, and medicines to achieve the best possible outcome. A personalized evaluation helps choose the most effective and safest treatment plan.

📌 TACE is often chosen when surgery is not possible and a strong local treatment is needed.

What Happens After Your Procedure?

After TACE:

  • You’ll stay in the hospital for 1–2 days
  • Fever, pain, or tiredness for a few days is common and expected
  • Medicines are given to control pain and nausea
  • You can usually return to normal activities in 5–7 days
  • Blood tests and scans are done to check liver function and tumor response
  • TACE may be repeated if needed, depending on response

Frequently Asked Questions (FAQs) – Transarterial Chemoembolization (TACE)

TACE is a minimally invasive cancer treatment that delivers chemotherapy directly into the blood vessels feeding a liver tumor and then blocks those vessels to cut off the tumor’s blood supply.

TACE is most commonly used for:

  • Primary liver cancer (hepatocellular carcinoma)
  • Tumors that have spread to the liver (in selected cases)

No. TACE is a catheter-based, minimally invasive procedure, not open surgery.

You won’t feel pain during the procedure. Pain, fever, or tiredness for a few days afterward is common and treated with medicines.

The procedure usually takes 1 to 2 hours, depending on the number and size of tumors.

Most patients stay in the hospital for 1 to 2 days for observation and symptom control.

TACE often shrinks or controls the tumor and slows disease progression. In some cases, it helps make surgery or liver transplant possible.

TACE is very effective in controlling liver tumors in many patients and is a standard treatment worldwide for inoperable liver cancer.

Some patients need one session, while others may need repeat treatments, depending on how the tumor responds.

Common side effects include fever, pain, nausea, and tiredness for a few days. Less common risks include infection, bleeding, liver function worsening, or non-target embolization. Serious complications are uncommon.

Post-embolization syndrome is a temporary reaction after TACE that includes fever, abdominal pain, nausea, and fatigue. It usually settles in a few days with medicines.

Yes. TACE is often combined with ablation, surgery, targeted therapy, or immunotherapy, depending on the cancer stage and treatment plan.

TACE is commonly used in patients with liver disease, but careful testing of liver function is done first to make sure it is safe.

Most patients return to normal daily activities within 5 to 7 days, depending on recovery and symptoms.

Yes. TACE is available in advanced cancer and interventional radiology centers across India.

Why Choose Transarterial Chemoembolization (TACE)?

  • Targeted cancer treatment
  • Minimally invasive
  • Fewer whole-body side effects
  • No big surgery
  • Can shrink and control tumors
  • Can be repeated if needed
  • Standard, proven liver cancer therapy

Looking for Advanced Treatment for Liver Tumors?

If you or your loved one has liver cancer or liver tumors not suitable for surgery, Transarterial Chemoembolization (TACE) can be a powerful treatment option.

Get expert advice and find out if TACE is right for you.
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